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Mission : To promote the health of the Ethiopian people by addressing priority public health system problems through problem-focused research.

Vision: To see healthy, productive and prosperous Ethiopians through mobilizing knowledge in the service of the health systems.

Objectives:
•Improve research on health system and
•Improve evidence-based decision making

Major activities:
•Identifying priority public health problems,
•Setting directions for health system research,
•Developing relevant and good-quality study protocols for health system research,
•Providing evidence based information to ensure relevance, quality, efficiency and ethical standards of public health service,
•Ensuring quality and utilization of research products.
•Providing evidence based information for sustainable capacity building of the health system, and
•Providing good governance to ensure health system research yields maximal benefits and minimal harm to health development.